• Circulating Metabolites Associated with Alcohol Intake in the European Prospective Investigation into Cancer and Nutrition Cohort 

      van Roekel, Eline H.; Trijsburg, Laura; Assi, Nada; Carayol, Marion; Achaintre, David; Murphy, Neil; Rinaldi, Sabina; Schmidt, Julie A.; Stepien, Magdalena; Kaaks, Rudolf; Kühn, Tilman; Boeing, Heiner; Iqbal, Khalid; Palli, Domenico; Krogh, Vittorio; Tumino, Rosario; Ricceri, Fulvio; Panico, Salavatore; Peeters, Petra H.; Bueno-De-Mesquita, Hendrik Bastiaan; Ardanaz, Eva; Lujan-Barroso, Leila; Quirós, José Ramón; Huerta, José María; Molina-Portillo, Elena; Dorronsoro, Miren; Tsilidis, Konstantinos K.; Riboli, Elio; Rostgaard-Hansen, Agnetha Linn; Tjønneland, Anne; Overvad, Kim; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Severi, Gianluca; Trichopoulou, Antonia; Karakatsani, Anna; Kotanidou, Anastasia; Håkansson, Anders; Malm, Johan; Weijenberg, Matty P.; Gunter, Marc J.; Jenab, Mazda; Johansson, Mattias; Travis, Ruth C.; Scalbert, Augustin; Ferrari, Pietro (Journal article; Peer reviewed, 2018-05-22)
      Identifying the metabolites associated with alcohol consumption may provide insights into the metabolic pathways through which alcohol may affect human health. We studied associations of alcohol consumption with circulating concentrations of 123 metabolites among 2974 healthy participants from the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Alcohol consumption at ...
    • Reliability of serum metabolites over a two-year period: A targeted metabolomic approach in fasting and non-fasting samples from EPIC 

      Carayol, Marion; Licaj, Idlir; Achaintre, David; Vineis, Paolo; Key, Timothy J.; Moret, N. Charlotte Onland; Scalbert, Augustin; Rinaldi, Sabina; Ferrari, Pietro (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-14)
      Objective Although metabolic profiles have been associated with chronic disease risk, lack of temporal stability of metabolite levels could limit their use in epidemiological investigations. The present study aims to evaluate the reliability over a two-year period of 158 metabolites and compare reliability over time in fasting and non-fasting serum samples. <p>Methods Metabolites were measured ...